Mucopolysaccharidosis IV A: Assignment of the human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) gene to chromosome 16q24

Journal Article · Tue Jun 01 00:00:00 EDT 1993 · Genomics; (United States)

DOI:https://doi.org/10.1006/geno.1993.1266· OSTI ID:7076773

Masuno, Mitsuo; Tomatsu, Shunji; Nakashima, Yoshihiro; Hori, Toshinori; Fukuda, Seiji; Masue, Michiya; Sukegawa, Kazuko; Orii, Tadao ^[1]

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1. Gifu Univ. School of Medicine (Japan)

Plasmid clones of three independent genomic fragments of the gene of human N-acetylgalactosamine-6-sulfate sulfatase (GALNS; EC 3.1.6.4) were utilized in a fluorescence in situ suppression hybridization study to assign the locus to chromosome 16q24. Enzyme assay for GALNS in a patient with del(16)(q22.1) confirmed this finding. 8 refs., 1 fig., 1 tab.

• OSTI ID: 7076773
• Journal Information: Genomics; (United States), Journal Name: Genomics; (United States) Vol. 16:3; ISSN GNMCEP; ISSN 0888-7543
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
AMINES
CARBOHYDRATES
CHROMOSOMES
DISEASES
DNA HYBRIDIZATION
ENZYMES
ESTERASES
GENES
GENETIC MAPPING
HUMAN CHROMOSOME 16
HUMAN CHROMOSOMES
HYBRIDIZATION
HYDROLASES
MAPPING
METABOLIC DISEASES
MUCOPOLYSACCHARIDES
ORGANIC COMPOUNDS
POLYSACCHARIDES
PROTEINS
SACCHARIDES