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Conformational characteristics of 1r,2t-dimethoxy-4c-methylcyclohexane. The nonadditivity of the conformational energy of the methyl group

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:7076406

It is usually considered that nonpolar alkyl substituents do not interact with other sufficiently distant groups. Therefore, the introduction of a methyl group into the molecule is sometimes used as a means for displacing the conformational equilibria of substituted cyclohexanes by a strictly defined amount. The authors have checked the accuracy of such an approach by comparing the conformational equilibria of trans-1,2-dimethoxycyclohexane and 1r,2t-dimethoxy-4c-methylcyclohexane. The ratio of the conformers was established by measuring the integral intensities of their signals in the low-temperature /sup 13/C NMR spectra. The spectra were measured on a Varian FT-70 spectrometer at 20 MHz with /sup 13/C-//sup 1/H/ proton decoupling.

Research Organization:
M. V. Lomonosov Moscow State Univ. (USSR)
OSTI ID:
7076406
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 23:5; ISSN JOCYA
Country of Publication:
United States
Language:
English

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