Detection of gastrointestinal bleeding with /sup 99m/Tc-labeled red blood cells

Journal Article · Thu Apr 01 00:00:00 EST 1982 · Semin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1016/S0001-2998(82)80005-6· OSTI ID:7070685

Winzelberg, G G; McKusick, K A; Froelich, J W; Callahan, R J; Strauss, H W

Using a modified in vivo /sup 99m/Tc red cell labeling technique, gastrointestinal bleeding scintigraphy was performed in 100 patients with GI bleeding. Sixty-two patients with melena or bright red blood per rectum had positive scintiscans. In comparison to results of angiography, endoscopy, surgery and contrast radiography, radionuclide scintigraphy correctly located the site of bleeding in 83% of patients. The procedures could be performed over a 24 hr period which increased the sensitivity of the test since 85% of the scintiscans were positive at one hr or greater after the onset of imaging. The procedure was more sensitive than angiography in detecting sources of GI bleeding. We conclude that GI bleeding scintigraphy /sup 99m/Tc-red cells in an accurate and effective method to detect upper and lower GI bleeding in patients with acute intermittent gastrointestinal bleeding.

• Research Organization: Department of Nuclear Medicine, Shadyside Hospital, Pittsburgh, PA
• OSTI ID: 7070685
• Journal Information: Semin. Nucl. Med.; (United States), Vol. 12:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
GASTROINTESTINAL TRACT
SCINTISCANNING
HEMORRHAGE
DIAGNOSIS
TECHNETIUM 99
DIAGNOSTIC USES
ERYTHROCYTES
ISOMERIC NUCLEI
LABELLED COMPOUNDS
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SYMPTOMS
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics