Mutagenic potential of sediments from the Grand Calumet River
Journal Article
·
· Bulletin of Environmental Contamination and Toxicology; (United States)
- Roswell Park Cancer Inst., Buffalo, NY (United States)
The Grand Calumet River/Indiana Harbor Canal is one of the International Joint Commission's Great Lakes Areas of Concern (AOC). Like many other AOCs, the Grand Calumet River is in a heavily industrialized area and has a history of chemical contamination. Many of the chemicals found in the industrial and municipal wastes that enter the waterway end up in sediment where they are concentrated to high levels. In order to assess the potential genotoxicity of sediments from the Grand Calumet River, the authors determined the mutagenic potential of organic extracts of sediments. The sediment extracts were assayed in the Salmonella/microsome mutagenicity test. In the Ames test, all ten sediment samples assayed were found to be mutagenic. In general, chemicals found in the sediments required metabolic activation before a positive mutagenic response was observed.
- OSTI ID:
- 7067020
- Journal Information:
- Bulletin of Environmental Contamination and Toxicology; (United States), Journal Name: Bulletin of Environmental Contamination and Toxicology; (United States) Vol. 47:2; ISSN 0007-4861; ISSN BECTA
- Country of Publication:
- United States
- Language:
- English
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