Definitive diagnosis of hepatic hemangiomas: MR imaging versus Tc-99m-labeled red blood cell SPECT

Journal Article · Sun Jul 01 04:00:00 EDT 1990 · Radiology; (USA)

DOI:https://doi.org/10.1148/radiology.176.1.2191377· OSTI ID:7063304

Birnbaum, B A; Weinreb, J C; Megibow, A J; Sanger, J J; Lubat, E; Kanamuller, H; Noz, M E; Bosniak, M A ^[1]

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1. New York Univ. Medical Center, NY (USA)

Thirty-seven patients with 69 suspected hemangiomas found by means of computed tomography (CT) and/or ultrasound were studied with both 0.5-T magnetic resonance (MR) imaging and single photon emission CT (SPECT) with technetium-99m-labeled red blood cells. Using a criterion of perfusion-blood pool mismatch, SPECT readers diagnosed 50 of 64 hemangiomas and all five nonhemangiomas (sensitivity, 78% (95% confidence interval, 0.664 - 0.864); accuracy, 80% (0.69 - 0.877)). Qualitative analysis of lesion signal intensity on T2-weighted spin-echo MR images allowed readers to diagnose 58 of 64 hemangiomas and four of five nonhemangiomas (sensitivity, 91% (0.814 - 0.96); accuracy, 90% (0.807 - 0.951)). Because of the significantly higher cost of MR imaging and its inability to categorically differentiate hemangiomas from hypervascular metastases, the authors consider SPECT to be the method of choice for diagnosing hepatic hemangiomas. MR imaging should be reserved for the diagnosis of lesions smaller than 2.0 cm and for those 2.5 cm and smaller adjacent to the heart or major hepatic vessels; in such cases MR imaging was found superior to SPECT.

• OSTI ID: 7063304
• Journal Information: Radiology; (USA), Journal Name: Radiology; (USA) Vol. 176:1; ISSN RADLA; ISSN 0033-8419
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
ACCURACY
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
EMISSION COMPUTED TOMOGRAPHY
ERYTHROCYTES
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIVER
MAMMALS
MAN
MATERIALS
NEOPLASMS
NMR IMAGING
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PRIMATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SENSITIVITY ANALYSIS
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TECHNETIUM 99
TECHNETIUM ISOTOPES
TOMOGRAPHY
VERTEBRATES
YEARS LIVING RADIOISOTOPES