Some reductions by hydride equivalents which involve radical pathways

Conference · Mon Sep 01 04:00:00 EDT 1986 · Am. Chem. Soc., Div. Pet. Chem., Gen. Pap., Prepr.; (United States)

OSTI ID:7043082

Tanner, D D; Singh, H K; Yang, D; Stein, A R

The mechanism for the reduction of aldehydes and ketones to their corresponding alcohols by reagents which donate hydrogen, hydride equivalents, may proceed by either homolytic or heterolytic pathways. It is difficult to differentiate mechanistically between a sequence of reactions proceeding by hydride transfer and one proceeding by electron transfer - hydrogen atom abstraction. A number of mechanistic probes is being used to study the details of these reactions. These include the reduction of a number of ketones: ..cap alpha..-haloketones, ..cap alpha..-cyclopropyl ketones and aryl ketones. The reduction of one type of probe, the ..cap alpha..-haloketone, is discussed. The emphasis of the discussion is on the reactions found to involved radical reactions whose pathways contain an electron transfer process.

• Research Organization: Dept. of Chemistry, Univ. of Alberta, Edmonton, Alberta
• OSTI ID: 7043082
• Report Number(s): CONF-860911-
• Conference Information: Journal Name: Am. Chem. Soc., Div. Pet. Chem., Gen. Pap., Prepr.; (United States) Journal Volume: 33:3
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
ALCOHOLS
ALDEHYDES
ALKYL RADICALS
ARYL RADICALS
CHEMICAL PREPARATION
CHEMICAL REACTION KINETICS
CHEMICAL REACTIONS
ELECTRON TRANSFER
ELEMENTS
HYDRIDES
HYDROGEN
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
KETONES
KINETICS
NONMETALS
ORGANIC COMPOUNDS
PERFORMANCE
PROPYL RADICALS
RADICALS
REACTION KINETICS
REDUCING AGENTS
REDUCTION
SYNTHESIS