Some reductions by hydride equivalents which involve radical pathways

Conference · Mon Sep 01 00:00:00 EDT 1986 · Am. Chem. Soc., Div. Pet. Chem., Gen. Pap., Prepr.; (United States)

OSTI ID:7043082

Tanner, D D; Singh, H K; Yang, D; Stein, A R

The mechanism for the reduction of aldehydes and ketones to their corresponding alcohols by reagents which donate hydrogen, hydride equivalents, may proceed by either homolytic or heterolytic pathways. It is difficult to differentiate mechanistically between a sequence of reactions proceeding by hydride transfer and one proceeding by electron transfer - hydrogen atom abstraction. A number of mechanistic probes is being used to study the details of these reactions. These include the reduction of a number of ketones: ..cap alpha..-haloketones, ..cap alpha..-cyclopropyl ketones and aryl ketones. The reduction of one type of probe, the ..cap alpha..-haloketone, is discussed. The emphasis of the discussion is on the reactions found to involved radical reactions whose pathways contain an electron transfer process.

• Research Organization: Dept. of Chemistry, Univ. of Alberta, Edmonton, Alberta
• OSTI ID: 7043082
• Report Number(s): CONF-860911-
• Journal Information: Am. Chem. Soc., Div. Pet. Chem., Gen. Pap., Prepr.; (United States), Vol. 33:3; Conference: 192. American Chemical Society national meeting, Anaheim, CA, USA, 7 Sep 1986
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ALCOHOLS
CHEMICAL PREPARATION
ALDEHYDES
CHEMICAL REACTION KINETICS
ELECTRON TRANSFER
REDUCTION
HYDRIDES
KETONES
ARYL RADICALS
HYDROGEN
PERFORMANCE
PROPYL RADICALS
RADICALS
REDUCING AGENTS
ALKYL RADICALS
CHEMICAL REACTIONS
ELEMENTS
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
KINETICS
NONMETALS
ORGANIC COMPOUNDS
REACTION KINETICS
SYNTHESIS
400201* - Chemical & Physicochemical Properties