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Mapping of the human CENP-B gene to chromosome 20 and the CENP-C gene to chromosome 12 by a rapid cycle DNA amplification procedure

Journal Article · · Genomics; (United States)
By optimizing the primer-annealing temperature in a rapid air cycling procedure, two human DNA sequences encoding centromere proteins B and C (CENP-B and CENP-C) were specifically amplified without any detectable amplification of highly homologous rodent DNA sequences. Using a panel of rodent/human hybrid DNA, the genes for humans CENP-B and CENP-C were conveniently mapped to chromosomes 20 and 12, respectively. 10 refs., 1 fig., 1 tab.
OSTI ID:
7035528
Journal Information:
Genomics; (United States), Journal Name: Genomics; (United States) Vol. 17:1; ISSN GNMCEP; ISSN 0888-7543
Country of Publication:
United States
Language:
English