Diagnostic impact of TL-201 imaging after dipyridamole on the clinical assessment of chest pain
Conference
·
· J. Nucl. Med.; (United States)
OSTI ID:7031438
With the information of history, coronary risk factors, and rest/exercise ECG of 60 patients without infarctions 6 physicians estimated the probability of coronary artery disease in % and the indication for coronary angiography on a 5-point scale. After receiving the results of Tl-201 imaging following dipyridamole (0.50 mg/kg iv) the physicians were asked to revise their estimations. Coronary angiograms were abnormal (>70% stenoses) in 43 patients and normal in 17. Tl-201 had a sensitivity of 74% and a specificity of 100%. In the patients with CAD the mean probability of CAD was increased after Tl-201 from 75.6% +- 20.2 to 82.9% +- 23.2 (10% change, p<0.001) and the mean indication for angiography from 4.3 +- 0.9 to 4.5 +- 0.9 (p<0.001). In the patients with normal coronary arteries the mean probability fell after Tl-201 from 36.7% +- 22.0 to 24.8% +- 21.0 (-32% change, p<0.001) and the indication from 2.7 +- 1.1 to 2.2 +- 1.2 (p<0.001). The authors conclude that Tl-201 imaging had a significant positive diagnostic impact in these patients and provided a significant improvement of the management in regard to coronary angiography. The influence on the estimations was comparably higher in patients without than with proven CAD.
- Research Organization:
- 1st Medical Dept., Univ. of Vienna
- OSTI ID:
- 7031438
- Report Number(s):
- CONF-850611-
- Conference Information:
- Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
BODY AREAS
CARDIOVASCULAR AGENTS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CHEST
CORONARIES
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DYNAMIC FUNCTION STUDIES
EVALUATION
HEART
LABELLED COMPOUNDS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PAIN
PATIENTS
RADIOISOTOPE SCANNING
RADIOLOGY
RADIOPHARMACEUTICALS
SCINTISCANNING
SENSITIVITY
SYMPTOMS
VASODILATORS
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
BODY AREAS
CARDIOVASCULAR AGENTS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CHEST
CORONARIES
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DYNAMIC FUNCTION STUDIES
EVALUATION
HEART
LABELLED COMPOUNDS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PAIN
PATIENTS
RADIOISOTOPE SCANNING
RADIOLOGY
RADIOPHARMACEUTICALS
SCINTISCANNING
SENSITIVITY
SYMPTOMS
VASODILATORS