Estimation of bone mineral content using gamma camera: A real possibility
Osteopenia and Osteoporosis are the diseases related to loss of bone minerals. At present, dual photon absorptiometry using a dedicated specially built scanner along with a very high source of Gd-153 is being used as a diagnostic tool for the early detection of bone loss. The present study was undertaken to explore the possibility that gamma cameras which are widely available in all Nuclear Medicine departments could be used successfully to evaluate bone mineral content. A Siemens LFOV gamma camera equipped with a converging collimator was used for this purpose. A fixed source (100 mCi) of Gd-153 was placed at the focal point of the collimator. A series of calcium chloride solutions of varying concentrations in plastic vials were placed near the center of the collimator and imaged both in air and water. Both 44 Kev and 100 Kev images were digitized in 128 x 128 matrices and processed in a CD and A Delta system attached to a VAX 11-750 computer. Uniformity corrections for each field of view were applied and the attenuation coefficients of calcium chloride for both peaks of Gd-153 were evaluated. In addition, due to the high count rate, corrections for the dead time losses were also found to be essential. An excellent concordance between the estimated Calcium contents and that actually present were obtained by this technic. In conclusion, use of gamma camera for the routine evaluation of Osteoporosis appears to be highly promising and worth pursuing.
- Research Organization:
- Div. of Nuclear Medicine, Dept. of Radiology, Long Island Jewish-Hillside Medical Center, New Hyde Park, NY
- OSTI ID:
- 7031328
- Report Number(s):
- CONF-850611-; TRN: 87-010731
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
BONE TISSUES
OSTEODENSITOMETRY
QUANTITATIVE CHEMICAL ANALYSIS
SCINTISCANNING
EVALUATION
GAMMA CAMERAS
OSTEOPOROSIS
DIAGNOSIS
BIOMEDICAL RADIOGRAPHY
COMPUTERIZED CONTROL SYSTEMS
GADOLINIUM 153
MINERALS
SKELETON
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BODY
CAMERAS
CHEMICAL ANALYSIS
CONNECTIVE TISSUE
CONTROL SYSTEMS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
GADOLINIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
SKELETAL DISEASES
TISSUES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques