PBB fed to adult female chickens: its effect on egg production, reproduction, viability of offspring, and residues in tissues and eggs

Journal Article · Sat Apr 01 00:00:00 EST 1978 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.7823283· OSTI ID:7028274

Polin, D; Ringer, R K

Two experiments with light breed laying chickens fed polybrominated biphenyl (PBB) as FireMaster FF-1. The first involved feeding PBB at dietary levels of 0.2, 1, 5, 25, 125, 625, and 3125 ppM, the second involved levels of 30, 45, 60, 90, and 120 ppM. Each group had 24 hens, and each experiment had a control group of 24 hens. PBB diets were fed for 5 weeks. Feed intake, production, reproduction, tissue residues and viability of offspring were monitored during that time and a subsequent 8 weeks. Production, hatchability, and viability of offspring were significantly affected by feeding PBB at 45 ppM. Marked inanition occurred at levels of 625 and 3125 ppM, and there was some loss of feed intake at 125 ppM. There was a return to normal production and hatchability in 3 to 4 weeks after PBB withdrawal of diets with levels of 125 ppM or less. Dose-response lines are presented for PBB in muscle, liver, kidney, adipose tissue, and eggs. Withdrawal curves for PBB from these tissues are also given.

• Research Organization: Michigan State Univ., East Lansing, MI (United States)
• OSTI ID: 7028274
• Journal Information: Environ. Health Perspect.; (United States), Vol. 23
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
ORGANIC BROMINE COMPOUNDS
BIOLOGICAL EFFECTS
DOSE-RESPONSE RELATIONSHIPS
ADIPOSE TISSUE
AROMATICS
CHICKENS
DIET
EGGS
FEMALES
FERTILITY
HATCHING
INGESTION
KIDNEYS
LIVER
MUSCLES
NUTRITIONAL DEFICIENCY
TISSUE DISTRIBUTION
VIABILITY
ANIMAL TISSUES
ANIMALS
BIRDS
BODY
CONNECTIVE TISSUE
DIGESTIVE SYSTEM
DISTRIBUTION
FOWL
GLANDS
INTAKE
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
TISSUES
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
551000 - Physiological Systems