Adenoid cystic salivary gland carcinoma: treatment with irradiation and surgery

Conference · Tue May 01 04:00:00 EDT 1984 · Radiology; (United States)

OSTI ID:7014471

Simpson, J R; Thawley, S E; Matsuba, H M

The recrods of 71 patients with adenoid cystic carcinoma of the salivary glands were reviewed to determine the dose response relationships for this aggressive tumor. Local control after treament was determined for all patients and analyzed with respect to extent of surgery and dose of radiation. Of 70 patients who were available for evaluation of local control, 28 (40%) had a local recurrence and 42 (60%) did not. The highest control rates were found in patients who underwent both radiation therapy and surgery. Patients who received a dose equal to or greater than 6,000 rad (60 Gy) in addition to surgery had significantly higher local control rates than those who received less than 6,000 rad (60 Gy). Distant metastases developed in 50% of patients regardless of local control, with the following distribution: 39% lung, 19% bone, and 10% disseminated soft-tissue metastases.

• Research Organization: Washington Univ. School of Medicine, St. Louis, MO
• OSTI ID: 7014471
• Conference Information: Journal Name: Radiology; (United States) Journal Volume: 151:2
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
CARCINOMAS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
EVALUATION
GLANDS
LUNGS
MEDICINE
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SALIVARY GLANDS
SKELETON
SURGERY
THERAPY