Irradiation and responsiveness to pain stimuli in rats

Journal Article · Sat Jan 01 00:00:00 EST 1994 · Life Sciences; (United States)

DOI:https://doi.org/10.1016/0024-3205(94)90120-1· OSTI ID:7007741

Rutten, E H.J.M.; Oosterveld, B J; Dirksen, R; Crul, B J.P.; Egmond, J van ^[1]

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1. Univ. of Nijmegen (Netherlands)

This study evaluates whether irradiation inhibits responses to pain in an animal model. The authors found that irradiation with doses of 10 Gy, 15 Gy and 17.5 Gy of the lumbar enlargement of the spinal cord inhibits behavioural responses to the stimulus of the hot-plate. These doses were otherwise without effects. This data is discussed in view of the effects of irradiation of living cells, and the authors propose that a modification of pain signal processing is accomplished. Similar considerations apply to the human condition.

• OSTI ID: 7007741
• Journal Information: Life Sciences; (United States), Vol. 54:23; ISSN 0024-3205
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
IONIZING RADIATIONS
BIOLOGICAL EFFECTS
PAIN
RESPONSE MODIFYING FACTORS
RADIATIONS
SYMPTOMS
560152* - Radiation Effects on Animals- Animals