Multidimensional gas chromatography with electron capture detection for the determination of toxic congeners in polychlorinated biphenyl mixtures

Journal Article · Tue Mar 01 04:00:00 EST 1988 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00156a021· OSTI ID:7005529

Duinker, J C; Schulz, D E; Petrick, G

A multidimensional gas chromatographic technique is suggested as a tool for effective separation of polychlorinated biphenyl (PCB) congeners which cannot be separated on a single SE 54 or other column. Two capillary columns are arranged in series, such that the second column receives only small preselected fractions eluting from the first column. The technique offers complete separation and increased sensitivity. The possibilities of the technique are demonstrated for toxic PCB congeners which were quantitated accurately for the first time in Clophen and Aroclor commercial mixtures and a seal blubber extract. The relative concentrations differed considerably between blubber extract and the commercial mixtures.

• Research Organization: Univ. of Kiel, Duesternbrooker Weg (West Germany)
• OSTI ID: 7005529
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 60:5; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
400105* -- Separation Procedures
550200 -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
ADIPOSE TISSUE
ANIMAL TISSUES
ANIMALS
AQUATIC ORGANISMS
AROMATICS
BLOOD VESSELS
BODY
CAPILLARIES
CAPTURE
CARDIOVASCULAR SYSTEM
CHEMICAL ANALYSIS
CHLORINATED AROMATIC HYDROCARBONS
CHROMATOGRAPHY
CONNECTIVE TISSUE
DATA
DISPERSIONS
ELECTRON CAPTURE
ENVIRONMENTAL MATERIALS
EXPERIMENTAL DATA
GAS CHROMATOGRAPHY
HALOGENATED AROMATIC HYDROCARBONS
INFORMATION
MAMMALS
MATERIALS
MIXTURES
NUMERICAL DATA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
PINNIPEDS
QUANTITATIVE CHEMICAL ANALYSIS
SEPARATION PROCESSES
TISSUES
TOXIC MATERIALS
VERTEBRATES