Silyl method for the synthesis of N-(organosulfonamidomethyl)lactams and imides

Journal Article · Thu Dec 10 04:00:00 EST 1987 · J. Gen. Chem. USSR (Engl. Transl.); (United States)

OSTI ID:7005351

Sergeev, V N; Shapovalenko, E P; Baukov, Yu I

For the synthesis of N-(sulfonamidomethyl) lactams and imides four variants of the silyl method are proposed, and of these two include the N-sulfonamidomethylation of N-silyl lactams and imides under the action of N-(chloromethyl) sulfonamides or their N-(siloxymethyl) equivalents and the other two consist in independent synthesis by the N-amidomethylaiton of N-silyl sulfonamides under the action of N-(chloromethyl) lactams or their N-(siloxymethyl) equivalents. The IR spectra of undiluted samples of the compounds as thin layers were determined with a Specord 75-IR spectrometer (NaBr, CaF/sub 2/). The PMR spectra were determined on a Tesla BS-467 spectrometer with a working frequency of 60 MHz.

• Research Organization: N. I. Pirogov Second Moscow State Medical Institute (USSR)
• OSTI ID: 7005351
• Journal Information: J. Gen. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Gen. Chem. USSR (Engl. Transl.); (United States) Vol. 57:6; ISSN JGCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
640302 -- Atomic
Molecular & Chemical Physics-- Atomic & Molecular Properties & Theory
74 ATOMIC AND MOLECULAR PHYSICS
ACTIVATION ENERGY
AMIDES
CATALYSTS
CATALYTIC EFFECTS
CHEMICAL REACTIONS
CHEMICAL SHIFT
COUPLING
COUPLING CONSTANTS
DEUTERIUM COMPOUNDS
ENERGY
HYDROGEN COMPOUNDS
IMIDES
INFRARED SPECTRA
INTERMEDIATE COUPLING
J-J COUPLING
LACTAMS
METHYLATION
NMR SPECTRA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SILICON COMPOUNDS
ORGANIC SULFUR COMPOUNDS
SPECTRA
SULFONATION
SYNTHESIS
ULTRAVIOLET SPECTRA