NIOSH special occupational-hazard review with control recommendations: Use of ethylene oxide as a sterilant in medical facilities

Technical Report · Mon Aug 01 04:00:00 EDT 1977

OSTI ID:7005286

Glaser, Z R

Ethylene oxide (ETO) is used extensively within health care facilities for sterilization of equipment and supplies which are heat sensitive. It is unique for this purpose. Alternative chemicals or processes have, in themselves, serious limitations or health hazards. Recent results of tests for mutagenesis have increased the concern for potential health hazards associated with exposure to ETO. In order to assess the potential for exposure and associated hazards, the National Institute for Occupational Safety and Health (NIOSH) has undertaken this Special Occupational Hazard Review. An assessment is made of the evidence for toxic effects of ETO, especially with respect to mutagenic, teratogenic and carcinogenic potentials. Additionally, a limited field survey was conducted by NIOSH to document the use, problems, and potential for human exposure in medical facilities. The results of the survey were in agreement with data made available by the American Hospital Association, the U.S. Army, other Federal agencies, and industrial and professional organizations. Based on the review, measures for control of occupational exposure are recommended.

• Research Organization: National Inst. for Occupational Safety and Health, Rockville, MD (USA). Priorities and Research Analysis Branch
• OSTI ID: 7005286
• Report Number(s): PB-90-181777/XAB; DHEW/PUB/NIOSH--77-200
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKENES
CARCINOGENS
CONTROL
ETHYLENE
HAZARDS
HEALTH HAZARDS
HYDROCARBONS
INDUSTRIAL MEDICINE
MEDICAL SUPPLIES
MEDICINE
MUTAGENS
OCCUPATIONAL EXPOSURE
OCCUPATIONAL SAFETY
ORGANIC COMPOUNDS
POLLUTION CONTROL
SAFETY
STERILIZATION