Technetium-99m dimercaptosuccinic acid uptake in long-term catheterized kidney. Comparison with renal function

Journal Article · Thu Mar 31 23:00:00 EST 1988 · Urology (Ridgewood, N.J.); (United States)

DOI:https://doi.org/10.1016/0090-4295(88)90092-1· OSTI ID:6995042

Higashihara, E; Tokuda, H; Kishi, H; Niijima, T; Okada, Y; Nishikawa, J; Iio, M

We studied 23 long-term catheterized kidneys in 14 patients. The uptake of /sup 99m/Tc acid (/sup 99m/Tc-DMSA) was measured at one- and two-hour intervals after injection, and the uptake was corrected for variations in renal depth. These values were compared with inulin, creatinine, and para-amino hippurate (PAH) clearances which were measured in each kidney by collecting urine through long-term catheterization. Correlation coefficient was obtained between PAH clearance corrected for the body surface area and the two-hour uptake of /sup 99m/Tc-DMSA. The correlation coefficients between the two-hour uptake of /sup 99m/Tc-DMSA and the clearance values are not significantly different from those between the one-hour uptake and the clearance values. Corrections of the uptake for variations in renal depth did not improve the correlation coefficients. The results show that /sup 99m/Tc-DMSA is an excellent method to estimate the renal plasma flow and the one-hour uptake without correction for renal depth is clinically sufficient to evaluate the split renal function.

• Research Organization: Univ. of Tokyo (Japan)
• OSTI ID: 6995042
• Journal Information: Urology (Ridgewood, N.J.); (United States), Journal Name: Urology (Ridgewood, N.J.); (United States) Vol. 31:4; ISSN URGYA
• Country of Publication: United States
• Language: English

Related Subjects

550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AMINO ACIDS
AZOLES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOHYDRATES
CARBOXYLIC ACIDS
CLEARANCE
COMPARATIVE EVALUATIONS
CREATININE
DICARBOXYLIC ACIDS
DYNAMIC FUNCTION STUDIES
EXCRETION
HETEROCYCLIC COMPOUNDS
HIPPURIC ACID
HOURS LIVING RADIOISOTOPES
IMIDAZOLES
IMINES
INTERMEDIATE MASS NUCLEI
INULIN
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
KIDNEYS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
PATIENTS
POLYSACCHARIDES
RADIOISOTOPES
RENAL CLEARANCE
SACCHARIDES
SUCCINIC ACID
TECHNETIUM 99
TECHNETIUM ISOTOPES
TRACER TECHNIQUES
UPTAKE
YEARS LIVING RADIOISOTOPES