Unique, one-step, double isomerization (2E, 4Z in equilibrium 2Z, 4E) of 6-oxo-2,4-heptadienoic acid catalyzed by maleylacetone cis-trans isomerase
Journal Article
·
· J. Am. Chem. Soc.; (United States)
In order to examine the structural requirements of the enzyme, maleylacetone cis-trans isomerase, the enzyme, 6-oxo-2,4-heptadienoic acids, and its methyl esters were synthesized to provide the four possible cis-trans isomeric skeletons. The compounds are reported. The reported results suggest that the enzyme binds maleylacetone in the region of the 6-oxo function as well as by its carboxyl group. 6 references, 1 figure.
- Research Organization:
- Brookhaven National Lab., Upton, NY
- OSTI ID:
- 6992733
- Journal Information:
- J. Am. Chem. Soc.; (United States), Journal Name: J. Am. Chem. Soc.; (United States) Vol. 106; ISSN JACSA
- Country of Publication:
- United States
- Language:
- English
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OSTI ID:7251095