Mass spectrometric identification and quantification of 5-methoxytryptophol in quail retina

Journal Article · Fri Dec 29 04:00:00 EST 1989 · Biochemical and Biophysical Research Communications; (USA)

DOI:https://doi.org/10.1016/0006-291X(89)92749-6· OSTI ID:6983946

Tsang, C W; Chan, S F; Lee, P P; Pang, S F ^[1]

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1. Department of Applied Biology Chemical Technology (Hong Kong)

The occurrence of 5-methoxytryptophol (5-MTL) in the quail retina was investigated by capillary column gas chromatography/mass spectrometry/selected ion monitoring using a deuterated internal standard. Based on ion intensity ratios in the mass spectra of pentafluoropropionyl and heptafluorobutyryl derivatives of 5-MTL and deuterated 5-MTL, 5-MTL was unequivocally identified in the quail retina. Similar to the circadian rhythm of retinal melatonin, retinal 5-MTL also exhibited a diurnal variation with high levels at mid-dark. However, no significant correlation between the diurnal levels of 5-MTL and melatonin was observed in the quail retina at mid-light or mid-dark.

• OSTI ID: 6983946
• Journal Information: Biochemical and Biophysical Research Communications; (USA), Journal Name: Biochemical and Biophysical Research Communications; (USA) Vol. 165:3; ISSN BBRCA; ISSN 0006-291X
• Country of Publication: United States
• Language: English

Related Subjects

550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AMINES
ANIMALS
AROMATICS
AZAARENES
AZOLES
BIRDS
BODY
BODY AREAS
CHEMICAL COMPOSITION
CHROMATOGRAPHY
DAILY VARIATIONS
DEUTERIUM
DISTRIBUTION
EYES
FACE
GAS CHROMATOGRAPHY
HEAD
HETEROCYCLIC COMPOUNDS
HYDROGEN ISOTOPES
INDOLES
ISOTOPE APPLICATIONS
ISOTOPES
LIGHT NUCLEI
MASS SPECTROSCOPY
MELATONIN
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRROLES
RETINA
SENSE ORGANS
SEPARATION PROCESSES
SPECTROSCOPY
STABLE ISOTOPES
TISSUE DISTRIBUTION
TRACER TECHNIQUES
TRYPTAMINES
VARIATIONS
VERTEBRATES