Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy
Journal Article
·
· American Journal of Human Genetics; (United States)
OSTI ID:6975546
- Univ. of Utah, School of Medicine, Salt Lake City, UT (United States)
Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.
- OSTI ID:
- 6975546
- Journal Information:
- American Journal of Human Genetics; (United States), Vol. 54:2; ISSN 0002-9297
- Country of Publication:
- United States
- Language:
- English
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