Stress scintigraphy using single-photon emission computed tomography in the evaluation of coronary artery disease

Journal Article · Tue May 01 04:00:00 EDT 1984 · Am. J. Cardiol.; (United States)

DOI:https://doi.org/10.1016/0002-9149(84)90073-0· OSTI ID:6975037

Nohara, R; Kambara, H; Suzuki, Y; Tamaki, S; Kadota, K; Kawai, C; Tamaki, N; Torizuka, K

Twenty-seven patients with angina pectoris, 24 with postmyocardial infarction angina and 7 with normal coronary arteries were examined by exercise thallium-201 emission computed tomography (SPECT) and planar scintigraphy. Exercise SPECT was compared with the reperfusion imaging obtained approximately 2 to 3 hours after exercise. The sensitivity and specificity of demonstrating involved coronary arteries by identifying the locations of myocardial perfusion defects were 96 and 87% for right coronary artery, 88 and 89% for left anterior descending artery (LAD) and 78 and 100% for left circumflex artery (LC). These figures are higher than those for planar scintigraphy (85 and 87% for right coronary artery, 73 and 89% for LAD and 39 and 100% for LC arteries). In patients with 3-vessel disease, sensitivity of SPECT (100, 88 and 75% for right coronary artery, LAD and LC, respectively) was higher than planar imaging (88, 63 and 31%, respectively), with a significant difference for LC (p less than 0.05). In 1, 2 and 0-vessel disease the sensitivity and specificity of the 2 techniques were comparable. Multivessel disease was more easily identified as multiple coronary involvement than planar imaging with a significant difference in 3-vessel disease (p less than 0.05). In conclusion, stress SPECT provides useful information for the identification of LC lesions in coronary heart disease, including 3-vessel involvement.

• Research Organization: Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan
• OSTI ID: 6975037
• Journal Information: Am. J. Cardiol.; (United States), Journal Name: Am. J. Cardiol.; (United States) Vol. 53:9; ISSN AJCDA
• Country of Publication: United States
• Language: English

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550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPUTERIZED TOMOGRAPHY
CORONARIES
DIAGNOSTIC TECHNIQUES
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MYOCARDIAL INFARCTION
ORGANS
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SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
THALLIUM ISOTOPES
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