The clinical value of bone and gallium scintigraphy for soft-tissue sarcomas of the extremities

Journal Article · Thu Mar 01 04:00:00 EST 1984 · J. Bone Jt. Surg., Am. Vol.; (United States)

OSTI ID:6965455

Kirchner, P T; Simon, M A

In a prospective study of forty-five patients, we evaluated the usefulness of bone and gallium scintigraphy prior to definitive surgery for a soft-tissue sarcoma in an extremity. Bone scintigraphy provides a baseline for staging and often reveals periosteal invasion that is not detected by routine radiographs. Blood-pool scintigraphy with bone tracers is very sensitive for a diagnosis of malignant disease. Gallium scintigraphy appeared to be a reliable preoperative indicator of malignant disease of soft tissue (sensitivity, 85 per cent; specificity, 92 per cent) and was useful for detecting the infrequent occult, non-pulmonary metastasis. Combined gallium and bone scintigraphy with blood-pool imaging provided a reliable prediction of the presence or absence of a malignant lesion in patients with a soft-tissue mass in an extremity. We recommend that bone and gallium scintigraphy be routinely used in the initial clinical staging of soft-tissue sarcomas.

• Research Organization: Department of Radiology, University of Chicago Hospitals and Clinics, Pritzker School of Medicine, Illinois
• OSTI ID: 6965455
• Journal Information: J. Bone Jt. Surg., Am. Vol.; (United States), Journal Name: J. Bone Jt. Surg., Am. Vol.; (United States) Vol. 66:3; ISSN JBJSA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
GALLIUM ISOTOPES
ISOTOPES
MATERIALS
NEOPLASMS
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
SARCOMAS
SCINTISCANNING
SKELETON