Abnormal scintigraphic evolution in AA hepatic amyloidosis

Journal Article · Tue Mar 01 00:00:00 EST 1988 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198803000-00015· OSTI ID:6954174

Lomena, F; Rosello, R; Pons, F; Grau, M; Garcia, A; Catafau, A; Setoain, J

A patient with AA amyloidosis secondary to ankylosing spondylitis showed intense liver uptake of Tc-99m MDP on bone imaging. The biopsy showed hepatic amyloid deposition. A repeat bone scan with Tc-99m MDP 1 year later was negative, although the clinical signs and liver function tests of the patient had not changed. A mechanism might exist, other than the affinity of amyloid to calcium, which would explain the extraosseous uptake of pyrophosphates and diphosphonates in organs and soft tissues affected by systemic amyloidosis.

• Research Organization: Nuclear Medicine Service, Barcelona (Spain)
• OSTI ID: 6954174
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 13:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
METABOLIC DISEASES
DIAGNOSIS
SKELETON
SCINTISCANNING
ERRORS
ISOMERIC NUCLEI
LIVER
PATIENTS
PYROPHOSPHATES
SPONDYLITIS
TECHNETIUM 99
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RHEUMATIC DISEASES
SKELETAL DISEASES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics