Chronicity and a low anteroposterior gradient of cerebral blood flow in schizophrenia

Journal Article · Thu Feb 01 00:00:00 EST 1990 · American Journal of Psychiatry; (USA)

OSTI ID:6938953

Mathew, R J; Wilson, W H ^[1]

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1. Duke Univ. Medical Center, Durham, NC (USA)

Regional cerebral blood flow (CBF) was measured with the 133xenon inhalation technique in 27 patients with schizophrenia of less than 5 years' duration and in 27 patients with schizophrenia of more than 12 years' duration, under resting conditions. Similar measurements were also performed in 54 normal control subjects matched for age and sex. Patients with schizophrenia of long duration had lower anteroposterior gradients of CBF than patients with schizophrenia of short duration and matched control subjects. Covarying out age and end-tidal levels of CO2 did not alter the results.

• OSTI ID: 6938953
• Journal Information: American Journal of Psychiatry; (USA), Vol. 147:2; ISSN 0002-953X
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
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