Assessment of human exposure to atrazine through the determination of free atrazine in urine

Journal Article · Mon Jan 01 04:00:00 EST 1990 · Bulletin of Environmental Contamination and Toxicology; (USA)

DOI:https://doi.org/10.1007/BF01702354· OSTI ID:6936683

Catenacci, G ^[1]; Maroni, M ^[2]; Cottica, D ^[3]; Pozzoli, L

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1. Univ. of Pavia (Italy)
2. Univ. of Milan (Italy)
3. Fondazione Clinical del Lavoro, Pavia (Italy)

Studies on metabolism and excretion of atrazine in man are not available in the literature. The present study has investigated human exposure to atrazine during its industrial production by means of assessment of ambient exposure and determination of free atrazine in urine. Four workers exposed to atrazine during its manufacture and packaging in a production plant, volunteered for the study. Atrazine was determined in airborne dust of the working environment obtained by personal sampling, on skin pads according to the WHO standard method, and on the skin of the hands of the workers by means of a washing procedure. Urine was collected before, during, and after exposure. A 24 hr collection before the first workshift, all the urine voided during the monitoring period, subdivided in 8 hr fractions; and one or more 12 hr samples after the end of the exposure period were collected.

• OSTI ID: 6936683
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (USA), Journal Name: Bulletin of Environmental Contamination and Toxicology; (USA) Vol. 44:1; ISSN 0007-4861; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
AIR SAMPLERS
AZINES
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CHEMICAL ANALYSIS
CLEARANCE
EQUIPMENT
EXCRETION
HETEROCYCLIC COMPOUNDS
MATERIALS
METABOLISM
OCCUPATIONAL EXPOSURE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PERSONNEL
QUANTITATIVE CHEMICAL ANALYSIS
SAMPLERS
SKIN ABSORPTION
TRIAZINES
UPTAKE
URINE
WASTES