Lead nephropathy: In vivo x ray fluorescence (XRF) for assessing body lead stores
Conference
·
OSTI ID:6935255
The EDTA lead mobilization test has proven of value in the diagnosis of renal disease due to lead (lead nephropathy) but is unsuitable for large scale studies in patients with end-stage renal disease. A rapid, safe, non-invasive technique for determining body lead stores by in vivo tibial x ray fluorescence (XRF) is described. These studies show that the chelation test can be replaced by in vivo XRF in patients with end-stage renal disease. XRF, for the first time, will permit epidemiologic studies of large populations which may be at risk for lead nephropathy from excessive exposure to environmental lead. 15 refs., 2 figs.
- Research Organization:
- Brookhaven National Lab., Upton, NY (USA); Veterans Administration Medical Center, East Orange, NJ (USA); University of Medicine and Dentistry of New Jersey, Newark (USA)
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 6935255
- Report Number(s):
- BNL-38902; CONF-8609203-2; ON: DE87003200
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
560300 -- Chemicals Metabolism & Toxicology
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
CHEMICAL ANALYSIS
CLEANING
DECONTAMINATION
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
EDTA
ELEMENTS
HAZARDS
HEALTH HAZARDS
LEAD
METALS
NEPHRITIS
NONDESTRUCTIVE ANALYSIS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
SKELETON
TIBIA
UROGENITAL SYSTEM DISEASES
USES
X-RAY EMISSION ANALYSIS
X-RAY FLUORESCENCE ANALYSIS
560300 -- Chemicals Metabolism & Toxicology
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
CHEMICAL ANALYSIS
CLEANING
DECONTAMINATION
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
EDTA
ELEMENTS
HAZARDS
HEALTH HAZARDS
LEAD
METALS
NEPHRITIS
NONDESTRUCTIVE ANALYSIS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
SKELETON
TIBIA
UROGENITAL SYSTEM DISEASES
USES
X-RAY EMISSION ANALYSIS
X-RAY FLUORESCENCE ANALYSIS