Changes in the blood system after extracorporeal irradiation

Journal Article · Sun Dec 01 04:00:00 EST 1985 · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)

DOI:https://doi.org/10.1007/BF00839299· OSTI ID:6929451

Bobkov, Y I; Alekseeva, L M; Appollonova, L A; Belopol'skii, A A; Golikov, V Y

The aim of this investigation was to study the effect of a single extracorporeal irradiation of blood (ECIB) on the cellular and biochemical composition of the blood and on activity of the factors of nonspecific immunity. Experiments were carried out on 16 mongrel dogs. A bypass tube used in the experiments was placed in a ''Perenos'' beta-apparatus, equipped with two IRUS-1 sources based on /sup 90/Sr and /sup 90/Y. The blood was irradiated for 3 h. Hematologic parameters changed in various ways as shown after ECIB. Also after ECIB, significant changes were found in the activity of several factors of natural immunity also shown here. An increase in activity of some factors of nonspecific immunoreactivity and stimulation of repair processes indicate that the ECIB method is a promising one for stimulating nonspecific defensive mechanisms in the body.

• Research Organization: Central Postgraduate Medical Institute, Moscow
• OSTI ID: 6929451
• Journal Information: Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Journal Name: Bull. Exp. Biol. Med. (Engl. Transl.); (United States) Vol. 100:7; ISSN BEXBA
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ANIMALS
ANTIGEN-ANTIBODY REACTIONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BLOOD
BLOOD CHEMISTRY
BLOOD COUNT
BODY FLUIDS
DAYS LIVING RADIOISOTOPES
DOGS
ENZYME ACTIVITY
EVEN-EVEN NUCLEI
EXTERNAL IRRADIATION
HEMATOLOGY
HOURS LIVING RADIOISOTOPES
IMMUNE REACTIONS
INTERMEDIATE MASS NUCLEI
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
RADIATION EFFECTS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RECOVERY
REPAIR
STRONTIUM 90
STRONTIUM ISOTOPES
THERAPY
VERTEBRATES
YEARS LIVING RADIOISOTOPES
YTTRIUM 90
YTTRIUM ISOTOPES