Radiation dose from radiopharmaceuticals contaminated with molybdenum-99

Journal Article · Sun May 01 00:00:00 EDT 1988 · J. Nucl. Med.; (United States)

OSTI ID:6924166

Shearer, D R; Pezzullo, J C; Moore, M M; Coleman, P; Frater, S I

Sixteen patients undergoing routine nuclear imaging procedures were injected with /sup 99m/Tc-labeled radiopharmaceuticals containing /sup 99/Mo which exceeded the recommended limit of 1 microCi of /sup 99m/Mo per mCi of /sup 99m/Tc. The kinetics of the resulting /sup 99/Mo distribution in 14 of these patients were studied over a period of several weeks. The mean biologic half-life (T 1/2b) ranged from about 19.3 days to 11.2 days depending on the model used. Similarly, the mean radiation dose to the liver ranged from approximately 0.02 rad/microCi of /sup 99/Mo to 0.05 microCi of /sup 99/Mo.

• Research Organization: Rhode Island Hospital, Providence (USA)
• OSTI ID: 6924166
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 29:5; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL HALF-LIFE
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
CONTAMINATION
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DOSES
DRUGS
DTPA
EVEN-ODD NUCLEI
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIVER
MOLYBDENUM 99
MOLYBDENUM ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
PATIENTS
RADIATION DOSES
RADIOISOTOPES
RADIOPHARMACEUTICALS
RADIOPROTECTIVE SUBSTANCES
TECHNETIUM 99
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES