Hydroxide-catalyzed synthesis of heterocyclic aromatic amine derivatives from nitriles
Journal Article
·
· J. Heterocycl. Chem.; (United States)
A generalized method for synthesizing a wide variety of heterocyclic aromatic amine derivatives from nitriles by use of hydroxide catalysts is presented. Nitrile dimers (3-aminocrotononitrile and dicyandiamide) and a dimer analog (anthranilonitrile) react with monomeric nitriles in the presence of hydroxide to form respectively, aminopyrimidines, diaminotriazines and aminoquinazolines.
- Research Organization:
- Oak Ridge Y-12 Plant, TN
- DOE Contract Number:
- W-7405-ENG-26
- OSTI ID:
- 6922791
- Journal Information:
- J. Heterocycl. Chem.; (United States), Vol. 19
- Country of Publication:
- United States
- Language:
- English
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