Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism

Journal Article · Fri Apr 01 04:00:00 EST 1988 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198804000-00006· OSTI ID:6922505

Ling, M C; Dake, M D; Okerlund, M D

Amiodarone is an iodinated antiarrhythmic agent that is effective in the treatment of atrial and ventricular arrhythmias. A number of side effects are seen, including pulmonary toxicity and thyroid dysfunction. A patient with both amiodarone-induced pneumonitis and hyperthyroidism who exhibited abnormal gallium activity in the lungs, as well as diffuse gallium uptake in the thyroid gland is presented. The latter has not been previously reported and supports the concept of iodide-induced thyroiditis with gallium uptake reflecting the inflammatory response.

• Research Organization: Univ. of California, San Francisco (USA)
• OSTI ID: 6922505
• Journal Information: Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 13:4; ISSN CNMED
• Country of Publication: United States
• Language: English

Related Subjects

560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GALLIUM ISOTOPES
GLANDS
HYPERTHYROIDISM
ISOTOPES
LUNGS
ORGANS
PNEUMONIA
RADIONUCLIDE KINETICS
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
THYROID
UPTAKE