Epidemiology of lung cancer in Xuan Wei, China: current progress, issues, and research strategies

Journal Article · Tue Mar 01 04:00:00 EST 1988 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1988.9935850· OSTI ID:6908085

Chapman, R S; Mumford, J L; Harris, D B; He, Z Z; Jiang, W Z; Yang, R D

In Xuan Wei, a rural Chinese county of about one million people, females' annual lung cancer mortality is China's highest, and males' is among China's highest. Xuan Wei's very high indoor air pollution levels (sometimes exceeding 20 mg/m3), residentially stable population, relatively uncomplicated lifestyle, and wide geographic variation in lung cancer mortality render it highly amenable to quantitative, interdisciplinary investigation of chemical carcinogens due to indoor air pollution. To date, epidemiologic findings reveal a closer association of lung cancer with the indoor burning of smoky coal (as opposed to smokeless coal or wood) than with tobacco use or occupation. Current aerometric, chemical, and toxicologic findings tend to confirm this association, though the specific carcinogenic constituents of Xuan Wei indoor air pollution have not yet been determined. Chinese and American investigators are conducting interdisciplinary field and laboratory investigations to quantify the lung cancer risk attendant on indoor air pollution relative to other factors, to measure and compare the characteristics of pollution from different Xuan Wei fuels, to determine the relative etiologic importance of pollution composition and concentration, and to develop quantitative relationships between air pollution dose and lung cancer risk.

• Research Organization: Environmental Protection Agency, Research Triangle Park, NC (USA)
• OSTI ID: 6908085
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 43:2; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

550900 -- Pathology
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AIR POLLUTION
ASIA
BODY
CARCINOGENS
CHINA
DISEASES
EPIDEMIOLOGY
INDOOR AIR POLLUTION
LUNGS
MORTALITY
NEOPLASMS
ORGANS
POLLUTION
RESPIRATORY SYSTEM
RISK ASSESSMENT
RURAL AREAS
TOXICITY