ACTH, corticosterone, and beta-endorphin in rat blood plasma after prolonged immobilization stress

Journal Article · Wed Jan 01 04:00:00 EST 1986 · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)

OSTI ID:6906920

Kiyatkin, E A; Amiragova, M G; Kushlinskii, N E; Polyntsev, Yu V

To assess functional relations between changes in ACTH, beta-endorphin (BE), and corticosterone (CS) levels, plasma concentrations of these hormones were studied in rats during the development of prolonged immobilization stress. Plasma hormone concentrations were determined by radioimmunoassay. The results were analyzed by standard statistical methods on a microcomputer. A particular feature about the kit used to determine BE was the presence of 50% cross-reactivity of the antiserum against beta-lipotrophin. To determine CS a highly specific antiserum produced by a laboratory was used.

• Research Organization: Academy of Medical Sciences of the USSR, Moscow
• OSTI ID: 6906920
• Journal Information: Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Journal Name: Bull. Exp. Biol. Med. (Engl. Transl.); (United States) Vol. 100:8; ISSN BEXBA
• Country of Publication: United States
• Language: English

Related Subjects

550101 -- Behavioral Biology-- Tracer Techniques
550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ACTH
ADRENAL HORMONES
ANIMALS
AUTONOMIC NERVOUS SYSTEM AGENTS
BIOLOGICAL EFFECTS
BIOLOGICAL FUNCTIONS
BIOLOGICAL MATERIALS
BIOLOGICAL STRESS
BLOOD
BLOOD PLASMA
BODY FLUIDS
CORTICOSTEROIDS
CORTICOSTERONE
DRUGS
ENDORPHINS
FUNCTIONS
GLUCOCORTICOIDS
HORMONES
HYDROXY COMPOUNDS
IMMUNE SERUMS
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
KETONES
MAMMALS
MATERIALS
NEUROREGULATORS
ORGANIC COMPOUNDS
PEPTIDE HORMONES
PITUITARY HORMONES
PREGNANES
QUANTITY RATIO
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNOLOGY
RATS
RETENTION
RODENTS
SECRETION
STEROID HORMONES
STEROIDS
SYNTHESIS
TRACER TECHNIQUES
VERTEBRATES