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Use of computed body tomography in malignant melanoma

Journal Article · · JAMA, J. Am. Med. Assoc.; (United States)

Malignant melanoma has no predictable clinical behavior. The Breslow depth and Clark's level of invasion are important prognostic factors, but their prognostic values are overshadowed by the presence of regional lymph node metastasis (stage III disease). The authors reviewed the CT scans and charts of 67 patients who had a confirmed diagnosis of malignant melanoma. Excluding patients with stage I disease, all others had histological evidence of metastatic disease shown in one or more sites by biopsy or necropsy specimens. In addition, in some patients metastatic disease was documented by clinical course and follow-up study in sites such as the brain, lung, and liver, where biopsies were not performed. They tried to ascertain any change in the extent of disease or any alteration in therapy that was based on the findings on the CT scan.

Research Organization:
Univ. of Maryland, Baltimore (USA)
OSTI ID:
6904206
Journal Information:
JAMA, J. Am. Med. Assoc.; (United States), Journal Name: JAMA, J. Am. Med. Assoc.; (United States) Vol. 259:19; ISSN JAMAA
Country of Publication:
United States
Language:
English

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