Depressed eruption rate of the rat maxillary incisor in a drug-induced uncompensated hemolytic state model

Journal Article · Thu Mar 01 00:00:00 EST 1990 · Journal of Dental Research; (USA)

DOI:https://doi.org/10.1177/00220345900690031501· OSTI ID:6896861

Giglio, M J; Sanz, A M; Bozzini, C E ^[1]

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1. Univ. of Buenos Aires (Argentina)

Female rats weighing about 180 g were separated into two groups. One group (A) received phenylhydrazine (PHZ) every other day during three weeks (for induction of an uncompensated hemolytic state), while the control group (C) received saline. The evidence for the establishment of the uncompensated hemolytic state was obtained by hematocrit value, reticulocyte count, and red-cell-volume-59Fe uptake. Body-weight gain (which is a measure of overall body growth rate), body-length gain (which is a measure of longitudinal skeletal growth rate), food intake, and maxillary incisor eruption rate (ER) were significantly depressed in rats of group A during the PHZ-injection period, in relation to rats of group C. These results indicate that anemia and/or associated factors depress ER, along with body growth and skeletal growth.

• OSTI ID: 6896861
• Journal Information: Journal of Dental Research; (USA), Vol. 69:3; ISSN 0022-0345
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
ERYTHROCYTES
HEMOLYSIS
HYDRAZINE
BIOLOGICAL EFFECTS
TEETH
CELL DIFFERENTIATION
ANEMIAS
ANIMAL GROWTH
BIOLOGICAL MODELS
BLOOD COUNT
INHIBITION
IRON 59
RATS
TRACER TECHNIQUES
WEIGHT
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DISEASES
EVEN-ODD NUCLEI
GROWTH
HEMIC DISEASES
INTERMEDIATE MASS NUCLEI
IRON ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LYSIS
MAMMALS
MATERIALS
NITROGEN COMPOUNDS
NUCLEI
ORAL CAVITY
PATHOLOGICAL CHANGES
RADIOISOTOPES
RODENTS
SYMPTOMS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques
550901 - Pathology- Tracer Techniques