Poly(4-vinylpyridine)-coated glassy carbon flow detectors
The performance of a thin-layer flow detector with a glassy carbon electrode coated with a film of protonated poly(4-vinylpyridine) is described. Substantial improvement in the selectivity of amperometric detection for liquid chromatography and flow injection systems is observed as a result of excluding cationic species from the surface. The detector response was evaluated with respect to flow rate, solute concentration, coating scheme, film-to-film reproducibility, and other variables. Despite the increase in diffusional resistance, low detection limits of ca. 0.04 and 0.10 ng of ascorbic acid and uric acid, respectively, are maintained. Protection from organic surfactants can be coupled to the charge exclusion effect by using a bilayer coating, with a cellulose acetate film atop the poly(4-vinylpyridine) layer. Applicability to urine sample is demonstrated.
- Research Organization:
- New Mexico State Univ., Las Cruces
- OSTI ID:
- 6881674
- Journal Information:
- Anal. Chem.; (United States), Vol. 59:5
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
36 MATERIALS SCIENCE
ASCORBIC ACID
AMPEROMETRY
LIQUID COLUMN CHROMATOGRAPHY
CARBON
PERFORMANCE
SURFACE COATING
COATINGS
ELECTRODES
POLYVINYLS
SURFACE PROPERTIES
PYRIDINES
URIC ACID
URINE
QUANTITATIVE CHEMICAL ANALYSIS
DIFFUSION
ELECTROCHEMISTRY
EXPERIMENTAL DATA
FLOW RATE
FLUID FLOW
INJECTION
SOLUTES
TRACE AMOUNTS
AROMATICS
AZAARENES
AZINES
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CHEMICAL ANALYSIS
CHEMISTRY
CHROMATOGRAPHY
DATA
DEPOSITION
ELEMENTS
HETEROCYCLIC COMPOUNDS
INFORMATION
INTAKE
MATERIALS
NONMETALS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANIC POLYMERS
POLYMERS
PURINES
SEPARATION PROCESSES
TITRATION
VITAMINS
WASTES
XANTHINES
400102* - Chemical & Spectral Procedures
400105 - Separation Procedures
360603 - Materials- Properties
400400 - Electrochemistry