Synthesis of oxazolines and oxazines

Patent · Tue Jan 17 04:00:00 EST 1995

OSTI ID:6879411

Benicewicz, B C; Mitchell, M A

A process is described for preparing an oxazoline or oxazine compound of the formula shown in the patent wherein X is an atom selected from the group of oxygen and sulfur, R is selected from the group consisting of C[sub 1--10] alkyl, C[sub 1--10] fluoroalkyl, aryl and substituted-aryl, and n is 2 or 3 comprising ring-closing a compound of the formula also shown in the patent wherein X is an atom selected from the group of oxygen and sulfur, R is selected from the group consisting of C[sub 1--10] alkyl, C[sub 1--10] fluoroalkyl, aryl, and substituted aryl, n is 2 or 3, and Y is a bromine or chlorine atom in the presence of a basic reagent consisting essentially of a fluoride salt supported on an inorganic solid substrate is disclosed together with the compounds, 5-bromomethyl-2-phenyl-1,3-oxazoline, 5-methylene-2-phenyl-1,3oxazine and 4,4-dimethyl-2-vinyl-1,3-oxazoline.

• Assignee: Dept. of Energy, Washington, DC (United States)
• Patent Number(s): A; US 5382665
• Application Number: PPN: US 8-032935
• OSTI ID: 6879411
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
BROMIDES
BROMINE COMPOUNDS
CHEMICAL PREPARATION
CHLORIDES
CHLORINE COMPOUNDS
FLUORIDES
FLUORINE COMPOUNDS
HALIDES
HALOGEN COMPOUNDS
MOLECULAR STRUCTURE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
SYNTHESIS