Distribution of exposure concentrations and doses for constituents of environmental tobacco smoke
- LaKind Associates (United States)
- M.E. Ginevan and Associates (United States)
- Johns Hopkins Univ., Baltimore, MD (United States). Dept. of Mathematical Sciences
- A.C. James and Associates (United States)
- Oak Ridge National Lab., TN (United States)
- TERA (United States)
- Sapphire Group, Inc., Bethesda, MD (United States)
The ultimate goal of the research reported in this series of three articles is to derive distributions of doses of selected environmental tobacco smoke (ETS)-related chemicals for nonsmoking workers. This analysis uses data from the 16-City Study collected with personal monitors over the course of one workday in workplaces where smoking occurred. In this article, the authors describe distributions of ETS chemical concentrations and the characteristics of those distributions for the workplace exposure. Next, they present population parameters relevant for estimating dose distributions and the methods used for estimating those dose distributions. Finally, they derive distributions of doses of selected ETS-related constituents obtained in the workplace for people in smoking work environments. Estimating dose distributions provided information beyond the usual point estimate of dose and showed that the preponderance of individuals exposed to ETS in the workplace were exposed at the low end of the dose distribution curve. The results of this analysis include estimations of hourly maxima and time-weighted average (TWA) doses of nicotine from workplace exposures to ETS and doses derived from modeled lung burdens of ultraviolet-absorbing particulate matter (UVPM) and solanesol resulting from workplace exposures to ETS (extrapolated from 1 day to 1 year).
- OSTI ID:
- 687380
- Journal Information:
- Risk Analysis, Journal Name: Risk Analysis Journal Issue: 3 Vol. 19; ISSN 0272-4332; ISSN RIANDF
- Country of Publication:
- United States
- Language:
- English
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