Extended X-ray absorption fine structure studies of Zn/sub 2/Fe/sub 2/ hybrid hemoglobins: absence of heme bond length changes in half-ligated species
Journal Article
·
· Biochemistry; (United States)
OSTI ID:6868954
Metal hybrid hemoglobins, in which Zn(II) replaces Fe(II), have been structurally characterized by extended X-ray absorption structure (EAFS) studies. Since Zn and Fe have very different K absorption edge energies, the structures of the ligated (Fe) and unligated (Zn) sites could be examined independently within a single molecule that mimics an intermediate ligation state. The observed EXAFS spectra and associated structural parameters are compared among the ligand free (..cap alpha..Zn)/sub 2/(..beta..Zn)/sub 2/, half-ligated (..cap alpha..FeCO)/sub 2/(..beta..Zn)/sub 2/ and (..cap alpha..Zn)/sub 2/(..beta..FeCO)/sub 2/, and fully ligated (..cap alpha..FeCO)/sub 2/(..beta..FeCO)/sub 2/ systems.
- Research Organization:
- Univ. of Rochester, NY (USA)
- OSTI ID:
- 6868954
- Journal Information:
- Biochemistry; (United States), Journal Name: Biochemistry; (United States) Vol. 25:13; ISSN BICHA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Proton nuclear magnetic resonance and spectrophotometric studies of nickel(II)-iron(II) hybrid hemoglobins
Nuclear magnetic resonance (NMR) studies of nickel-iron hybrid hemoglobins (Hb)
Iron-sulfur bond lengths in ferrous-CO heme complexes as a function of sulfur donor type
Journal Article
·
Tue Apr 21 00:00:00 EDT 1987
· Biochemistry; (United States)
·
OSTI ID:5598932
Nuclear magnetic resonance (NMR) studies of nickel-iron hybrid hemoglobins (Hb)
Conference
·
Thu May 01 00:00:00 EDT 1986
· Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)
·
OSTI ID:5206735
Iron-sulfur bond lengths in ferrous-CO heme complexes as a function of sulfur donor type
Journal Article
·
Tue Nov 04 23:00:00 EST 1986
· Inorg. Chem.; (United States)
·
OSTI ID:6713360
Related Subjects
550200* -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
CARBOXYLIC ACIDS
ELEMENTS
GLOBIN
HEME
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
IRON
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
SPECTROSCOPY
STRUCTURAL CHEMICAL ANALYSIS
TRANSITION ELEMENTS
X-RAY SPECTROSCOPY
ZINC
59 BASIC BIOLOGICAL SCIENCES
CARBOXYLIC ACIDS
ELEMENTS
GLOBIN
HEME
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
IRON
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
SPECTROSCOPY
STRUCTURAL CHEMICAL ANALYSIS
TRANSITION ELEMENTS
X-RAY SPECTROSCOPY
ZINC