In vitro cytotoxicities of inorganic lead and di- and trialkyl lead compounds to fish cells

Journal Article · Thu Mar 01 04:00:00 EST 1990 · Bulletin of Environmental Contamination and Toxicology; (USA)

DOI:https://doi.org/10.1007/BF01701229· OSTI ID:6867215

Babich, H ^[1]; Borenfreund, E ^[2]

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1. Rockefeller Univ., New York, NY (USA) Yeshiva Univ., New York, NY (USA)
2. Rockefeller Univ., New York, NY (USA)

Although there has been much research on the effects of inorganic lead on the aquatic biota, less is known on the environmental impact of organolead compounds. Organolead compounds are primarily of anthropogenic origin, with the largest consumption of organolead being the use of tetraalkyl Pb as an antiknock additive in gasoline. Once deposited into aquatic environments the tetraalkyl Pb compounds may be degraded to tri- and dialkyl Pb species and then finally to Pb{sup 2+}. Di- and trialkyl Pb species are used as biocides and may enter aquatic ecosystems through runoff from terrestrial environments. This study evaluated the relative cytotoxicities of di- and trialkyl Pb compounds to fish cells in culture.

• OSTI ID: 6867215
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (USA), Journal Name: Bulletin of Environmental Contamination and Toxicology; (USA) Vol. 44:3; ISSN 0007-4861; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACETATES
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL EFFECTS
CARBOXYLIC ACID SALTS
CELL CULTURES
CELL KILLING
CHLORIDES
CHLORINE COMPOUNDS
FISHES
HALIDES
HALOGEN COMPOUNDS
LEAD CHLORIDES
LEAD COMPOUNDS
LEAD HALIDES
LEAD NITRATES
NITRATES
NITROGEN COMPOUNDS
OXYGEN COMPOUNDS
TOXICITY
VERTEBRATES