Detection of coronary artery disease - comparison of exercise stress radionuclide angiocardiography and thallium stress perfusion scanning

Journal Article · Tue Jan 01 00:00:00 EST 1980 · Am. J. Cardiol.; (United States)

DOI:https://doi.org/10.1016/S0002-9149(80)80001-4· OSTI ID:6867151

Jengo, J A; Freeman, R; Brizendine, M; Mena, I

Exercise thallium scanning and stress radionuclide angiography were compared in 16 normal subjects and 42 patients with more than 75% coronary arterial obstruction in studies using upright exercise on a bicycle ergometer. Studies at rest were subsequently obtained. Exercise thallium scans in the control group were normal in 15 and showed a defect in 1. Ejection fraction increased in all 16. During exercise, regional wall motion increased uniformly. In the group with coronary artery disease, thallium scanning revealed a new defect in the distribution of the involved arteries in 24 patients. In 15 who had a defect at rest, no new defect developed, but in 9 of the 15 new segmental wall motion defects were evident on radionuclide angiography. With exercise, ejection fraction decreased slightly. Regional wall motion abnormalities developed in the areas corresponding to thallium defects in all. Thallium scanning had a 93% and radionuclide angiography a 98% sensitivity value in detecting coronary artery disease. The respective specificity values were 94 and 100%. In patients with prior myocardial infarction who manifested new exercise abnormalities, 50% showed new thallium defects and 81% new wall motion defects.

• Research Organization: California, University, Los Angeles Medical Center, Torrance; St. Mary Medical Center, Long Beach, Calif.
• OSTI ID: 6867151
• Journal Information: Am. J. Cardiol.; (United States), Vol. 45
• Country of Publication: United States
• Language: English

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