Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Comparison of magnetic resonance imaging and radionuclide imaging in the evaluation of renal transplant failure

Journal Article · · Clin. Nucl. Med.; (United States)
; ; ;

Magnetic resonance imaging (MRI) was compared with radionuclide scintigraphy (RNS) in 16 patients with renal transplants undergoing renal failure to determine which modality could best discriminate between rejection, acute tubular necrosis (ATN), and cyclosporin nephrotoxicity (CN). Although all rejecting transplants had reduced corticomedullary differentiation (CMD) on T1-weighted MR images, four of five cases of ATN had appearances that could not be distinguished from rejection. A normal CMD suggests nonrejection, but diminished CMD is nonspecific. Tc-99m DTPA/I-131 hippuran RNS was superior to MRI in differentiating rejection from ATN. Although ATN and CN have similar RNS patterns, this distinction can usually be made based on the clinical time course. Other potential uses of MRI in the evaluation of the renal transplants are discussed.

Research Organization:
Cedars-Sinai Medical Center, Los Angeles, CA (USA)
OSTI ID:
6858941
Journal Information:
Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 13:4; ISSN CNMED
Country of Publication:
United States
Language:
English

Similar Records

Magnetic resonance imaging of renal transplants
Journal Article · Fri Nov 30 23:00:00 EST 1984 · AJR, Am. J. Roentgenol.; (United States) · OSTI ID:6119051
Correlation of radionuclide findings in renal transplants with interstitial cellular infiltrations
Conference · Wed May 01 00:00:00 EDT 1985 · J. Nucl. Med.; (United States) · OSTI ID:5939006
Magnetic resonance imaging of the kidneys
Journal Article · Fri Nov 30 23:00:00 EST 1984 · AJR, Am. J. Roentgenol.; (United States) · OSTI ID:5983390

Related Subjects

550600 -- Medicine
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DTPA
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
MAGNETIC RESONANCE
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
RESONANCE
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
TRANSPLANTS
UROGENITAL SYSTEM DISEASES
YEARS LIVING RADIOISOTOPES