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Demonstration of bacteriocin activity in bovine and bison strains of Pasteurella multocida. [UV radiation]

Journal Article · · Am. J. Vet. Res.; (United States)
OSTI ID:6858810
Of 33 strains of Pasteurella multocida examined, 14 showed bacteriocin activity and 17 were susceptible to bacteriocin. The activity was increased by about twofold if the cultures were induced with ultraviolet radiation; however, no increase in bacteriocin activity was observed if the potential producer strains were induced with mitomycin C. The bacteriocin activity of potential producer strains was increased if CaCl/sub 2/ was incorporated in the medium. The patterns of bacteriocin susceptibility indicate that these substances may ultimately contribute to a typing scheme for the species. An extra-chromosomal genetic element was not detected when a potential producer strain was not detected when a potential producer strain was tested by the dye-buoyant density gradient method. This fact suggests that the genetic material responsible for bacteriocin activity in P multocida is located on the host chromosome proper.
Research Organization:
Michigan State Univ., Lansing
OSTI ID:
6858810
Journal Information:
Am. J. Vet. Res.; (United States), Journal Name: Am. J. Vet. Res.; (United States) Vol. 38:8; ISSN AJVRA
Country of Publication:
United States
Language:
English