Error bounds for MEG and EEG source localization

Conference · Wed Jan 01 04:00:00 EST 1992

OSTI ID:6855257

Mosher, J C ^[1]; Spencer, M E ^[2]; Leahy, R M ^[3]

---

1. University of Southern California, Los Angeles, CA (United States). Signal and Image Processing Inst. Los Alamos National Lab., NM (United States)
2. University of Southern California, Los Angeles, CA (United States). Signal and Image Processing Inst. TRW Space and Defense, One Space Park, Redondo Beach, CA (United States)
3. University of Southern Californ

Localization error bounds are presented for both EEG and MEG as graphical error contours for a 37 sensor arrangement. Both one and two dipole cases were examined for all possible dipole orientations and locations within a head quadrant. The results show a strong dependence on absolute dipole location and orientation. The results also show that fusion of the EEG and MEG measurements into a combined model reduces the lower bound. A Monte-Carlo simulation was performed to check the tightness of the bounds for a selected case. The simple head model, the white and relatively low power noise, and the few relatively strong dipoles were all selected in this study as optimistic conditions to establish possibly fundamental resolution limits for any localization effort.

• Research Organization: Los Alamos National Lab., NM (United States)
• Sponsoring Organization: DOE; USDOE, Washington, DC (United States)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 6855257
• Report Number(s): LA-UR-92-3646; CONF-9210231--2; ON: DE93003794
• Country of Publication: United States
• Language: English

Related Subjects

440101* -- Radiation Instrumentation-- General Detectors or Monitors & Radiometric Instruments
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
BIOT-SAVART LAW
CALCULATION METHODS
DIAGNOSTIC TECHNIQUES
DIPOLES
ELECTROENCEPHALOGRAPHY
ERRORS
IMAGE PROCESSING
MONTE CARLO METHOD
MULTIPOLES
PROCESSING