Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): Localization to chromosome 2 and identification of a simple tandem repeat polymorphism
Journal Article
·
· Genomics; (United States)
- Univ. of Chicago, IL (United States)
The gene encoding the human G-protein-coupled inwardly rectifying potassium channel designated GIRK1 (gene symbol, KCNJ3) was mapped to chromosome 2 by analyzing its segregation in a panel of human-hamster somatic cell hybrids. This assignment was confirmed by fluorescence in situ hybridization to metaphase chromosomes, and the gene was further localized to band 2q24.1. A highly informative simple tandem repeat DNA polymorphism of the form (CA)[sub n] was identified and used to localize KCNJ3 within the genetic map of the long arm of chromosome 2. 8 refs., 1 fig., 2 tabs.
- OSTI ID:
- 6853724
- Journal Information:
- Genomics; (United States), Vol. 21:1; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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