Histoplasmosis of the adrenal glands studied by CT

Journal Article · Thu Mar 01 04:00:00 EST 1984 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.150.3.6695079· OSTI ID:6849701

Wilson, D A; Muchmore, H G; Tisdal, R G; Fahmy, A; Pitha, J V

Computed tomography (CT) of the adrenal glands was performed on seven patients who had histologically proved disseminated histoplasmosis. All seven patients showed some degree of adrenal gland abnormality. The range of CT findings included minimal enlargement with faint flecks of calcium, moderate enlargement with focal low attenuation nodules, and massive enlargement with large areas of necrosis or dense calcification. The changes in each patient were bilateral and symmetrical. Adrenal gland shape was usually preserved. Finding of percutaneous adrenal biopsy, which was performed under CT guidance, made the diagnosis in one patient. Five of seven patients had adrenal insufficiency. It is concluded that the diagnosis of disseminated histoplasmosis should be considered in any patient who has bilateral adrenal gland enlargement and who resides in an endemic area, especially if there is evidence of adrenal insufficiency.

• Research Organization: Univ. of Oklahoma Health Sciences Center, Oklahoma City
• OSTI ID: 6849701
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 150:3; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ADRENAL GLANDS
BODY
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
FUNGAL DISEASES
GLANDS
INFECTIOUS DISEASES
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
TOMOGRAPHY