Images of the brain: past as prologue
Journal Article
·
· J. Nucl. Med.; (United States)
OSTI ID:6845195
The invention of the Anger scintillation camera and the development of /sup 99m/Tc tracers brought about a tenfold increase in nuclear brain scanning between 1963 and 1973, an increase that plateaued with the introduction of x-ray computed tomography. A second growth curve began in 1976 at which time there were four PET centers in the United States, a number that grew to 60 worldwide over the next decade. PET, SPECT, MRI, and MRS are leading us into a new era of in vivo brain chemistry, based on regional bioenergetics and neurotransmission. The immediate impact is in epilepsy, stroke, brain tumors and the dementias, with psychiatric diseases becoming a major focus of research. Receptivity has become a biochemical as well as a psychological approach to mental functions. The finding of elevated D2 dopamine receptors in schizophrenia in living patients may be the forerunner of a new biochemical approach to psychiatry.
- Research Organization:
- Johns Hopkins Medical Institutions, Baltimore, MD
- OSTI ID:
- 6845195
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 12; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BRAIN
CAMERAS
CENTRAL NERVOUS SYSTEM
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
FORECASTING
GAMMA CAMERAS
HISTORICAL ASPECTS
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAGNETIC RESONANCE
MENTAL DISORDERS
NERVOUS SYSTEM
NUCLEAR MAGNETIC RESONANCE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RESONANCE
TECHNETIUM 99
TECHNETIUM ISOTOPES
TOMOGRAPHY
YEARS LIVING RADIOISOTOPES
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BRAIN
CAMERAS
CENTRAL NERVOUS SYSTEM
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
FORECASTING
GAMMA CAMERAS
HISTORICAL ASPECTS
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAGNETIC RESONANCE
MENTAL DISORDERS
NERVOUS SYSTEM
NUCLEAR MAGNETIC RESONANCE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RESONANCE
TECHNETIUM 99
TECHNETIUM ISOTOPES
TOMOGRAPHY
YEARS LIVING RADIOISOTOPES