Accuracy of ejection fraction by nuclear stethoscope in left ventricular aneurysm
The Nuclear Stethoscope has been shown to reliably determine left ventricular (LV) ejection fraction (EF). However, the instrument differs from standard Anger camera techniques in that (1) it uses a single region-of-interest for assessing changes in radioactive counts, and (2) it is positioned ''blindly'' over the LV. For these reasons its accuracy in patients (pts) with LV aneurysm might be less than in pts with normal or less abnormal wall motion. The authors studied 30 consecutive pts by both standard dated blood pool (GBP) scanning and Nuclear Stethoscope (probe). Twenty pts had normal or mildly abnormal wall motion and 10 had focal dyskinesis (aneurysm). The probe studies were performed by one of two experienced operators who were unaware of GBP results, and in 19 pts there were two separate probe acquisitions. Studies were performed in alternating sequence (i.e., GBP or probe first). GBP scans were acquired for 6 million counts spanning 24 frames, and probe studies for 60 or 120 sec (depending on the observed counting rate) in the ventricular function mode. Overall, the EF's ranged from 0.11 to 0.82, and the values from GBP and probe studies were highly correlated (r=O.93). In the 19 pts with two probe studies there was good interobserver reproducibility (r=0.96, SEE=0.05). The correlation between GBP and probe EF was similar in the 10 aneurysm pts (r=0.92, SEE=0.07) and the 20 pts with normal or mildly abnormal wall motion (r=0.92, SEE=0.08). The slope in the aneurysm pts (0.92) was not significantly different from that in the pts without aneurysm (0.97). These data confirm the accuracy of the Nuclear Stethoscope for determining EF and demonstrate its specific reliability in pts with LV aneurysm.
- Research Organization:
- Univ. of Pennsylvania, Philadelphia, PA
- OSTI ID:
- 6844292
- Report Number(s):
- CONF-840619-
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 25:5; Conference: 31. annual meeting of the Society of Nuclear Medicine, Los Angeles, CA, USA, 5 Jun 1984
- Country of Publication:
- United States
- Language:
- English
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