Biological characterization of radiation exposure and dose estimates for inhaled uranium milling effluents
- Inhalation Toxicology Research Inst., Albuquerque, NM (USA)
The problems addressed are the protection of uranium mill workers from occupational exposure to uranium through routine bioassay programs and the assessment of accidental worker exposures. Comparisons of chemical properties and the biological behavior of refined uranium ore (yellowcake) are made to identify important properties that influence uranium distribution patterns among organs. These studies will facilitate calculations of organ doses for specific exposures and associated health risk estimates and will identify important bioassay procedures to improve evaluations of human exposures. Samples of airborne uranium from operating mills and deposition models were used to predict appreciable deposition rates in the upper respiratory tract of workers, if respiratory protection were not used. A biokinetic model of retention and excretion of yellowcake inhaled by Beagle dogs was developed. Comparison of the results with available data from human exposures showed that organ burdens in an exposed worker can be estimated from urinary bioassay results and in vivo counting, if the chemical composition, or soluble fraction, of the inhaled yellowcake is known. 34 refs., 31 figs., 24 tabs.
- Research Organization:
- Nuclear Regulatory Commission, Washington, DC (USA). Div. of Regulatory Applications; Inhalation Toxicology Research Inst., Albuquerque, NM (USA)
- Sponsoring Organization:
- NRC
- OSTI ID:
- 6820217
- Report Number(s):
- NUREG/CR-5489; LMF--124; ON: TI90012914
- Country of Publication:
- United States
- Language:
- English
Similar Records
Biological characterization of radiation exposure and dose estimates for inhaled uranium milling effluents. Annual progress report April 1, 1982-March 31, 1983
Biological characterization of radiation exposure and dose estimates for inhaled uranium milling effluents. Annual progress report, April 1, 1983-March 31, 1984
Related Subjects
11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACCIDENTS
ACTINIDE COMPOUNDS
AMMONIUM COMPOUNDS
AMMONIUM URANATES
ANIMALS
BEAGLES
BIOASSAY
CHALCOGENIDES
CHEMICAL PROPERTIES
DOCUMENT TYPES
DOGS
DOSE EQUIVALENTS
HAZARDS
HEALTH HAZARDS
INHALATION
INTAKE
MAMMALS
MILL TAILINGS
OCCUPATIONAL EXPOSURE
OXIDES
OXYGEN COMPOUNDS
PERSONNEL
PROGRESS REPORT
RADIATION PROTECTION
RATS
RETENTION
RODENTS
SOLID WASTES
TAILINGS
URANATES
URANIUM COMPOUNDS
URANIUM OXIDES
VERTEBRATES
WASTES