Biologic gastric emptying time in diabetic patients, using Tc-99m-labeled resin-oatmeal with and without metoclopramide

Conference · Fri Oct 31 23:00:00 EST 1980 · J. Nucl. Med.; (United States)

OSTI ID:6819495

Domstad, P A; Kim, E E; Coupal, J J; Beihn, R; Yonts, S; Choy, Y C; Mandelstam, P; DeLand, F H

Biologic gastric emptying time (BGET) was measured in 24 patients with severe diabetes mellitus complicated by vascular damage and peripheral or sensory neuropathy. This population had a BGET of 192 +- 32.9 min (mean +- s.e.m. normal 40 to 85 min). Patients with diabetic gastroenteropathy had prolongation of BGET to 295 +- 45 (p < 0.05). Metoclopramide significantly shortened BGET in this subgroup to 101 +- 40 min, with return to normal values in eight of the 12 patients given the drug. The Tc-99m-labeled resin-oatmeal test meal used as described in this study provides a reliable measure of BGET and of the response to metoclopramide.

• Research Organization: Univ. of Kentucky, Lexington
• OSTI ID: 6819495
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 21:11; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

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551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AMIDES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY FLUIDS
COUNTING TECHNIQUES
DATA ANALYSIS
DIABETES MELLITUS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DIET
DIGESTIVE SYSTEM
DISEASES
DYNAMIC FUNCTION STUDIES
ENDOCRINE DISEASES
FOOD
GASTRIC ACID
GASTROINTESTINAL TRACT
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MATERIALS
METABOLIC DISEASES
METABOLISM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC POLYMERS
PATIENTS
PETROCHEMICALS
PETROLEUM PRODUCTS
POLYMERS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESINS
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
TIME DEPENDENCE
USES
YEARS LIVING RADIOISOTOPES