Abnormal lung gallium-67 uptake preceding pulmonary physiologic impairment in an asymptomatic patient with Pneumocystis carinii pneumonia

Journal Article · Tue May 01 04:00:00 EDT 1990 · Chest; (USA)

DOI:https://doi.org/10.1378/chest.97.5.1261· OSTI ID:6809413

Reiss, T F; Golden, J ^[1]

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1. Univ. of California, San Francisco (USA)

Pneumocystis carinii pneumonia was suggested by a diffuse, bilateral pulmonary uptake of gallium-67 in an asymptomatic, homosexual male with the antibody to the immunodeficiency virus (HIV) who was undergoing staging evaluation for lymphoma clinically localized to a left inguinal lymph node. Chest radiograph and pulmonary function evaluation, including lung volumes, diffusing capacity and arterial blood gases, were within normal limits. Bronchoalveolar lavage revealed Pneumocystis carinii organisms. In this asymptomatic, HIV-positive patient, active alveolar infection, evidenced by abnormal gallium-67 scanning, predated pulmonary physiologic abnormalities. This observation raises questions concerning the natural history of this disease process and the specificity of physiologic tests for excluding disease. It also has implications for the treatment of neoplasia in the HIV-positive patient population.

• OSTI ID: 6809413
• Journal Information: Chest; (USA), Journal Name: Chest; (USA) Vol. 97:5; ISSN CHETB; ISSN 0012-3692
• Country of Publication: United States
• Language: English

Related Subjects

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AIDS
BETA DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
IMAGE PROCESSING
IMMUNE SYSTEM DISEASES
INFECTIOUS DISEASES
INTERMEDIATE MASS NUCLEI
ISOTOPES
LUNGS
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PNEUMONIA
PROCESSING
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
UPTAKE
VIRAL DISEASES