Chloroperoxidase mediated halogenation of phenols
- Univ. of Pittsburgh, PA (USA)
Halophenols are among the many varied types of halogenated organic compounds occurring in the ecosystem. Primarily because of pollution research, the chlorophenols found in most environmental samples are believed to be the result of man-related activities. However, several of the halophenols also have a natural origin. Since environmental investigation of halogenated pollutants usually leads to the ultimate source(s) of these substances, careful assessment must be made regarding the presence, causes and effects of halophenols found in the biosphere. The emerging picture strongly indicates that many organisms contain haloperoxidase enzymes which catalyze the formation of a carbon-halogen covalent bond leading to the formation of halogenated natural products. In this study, the authors employed a fungal enzyme, chloroperoxidase (CPO) obtained from Caldariomyces fumago. Chloroperoxidase has been well utilized as a model in the study of biological halogenation. Their intent was to use the enzyme as a means to predict potential halogenation of phenols in the ecosystem.
- OSTI ID:
- 6808549
- Journal Information:
- Bulletin of Environmental Contamination and Toxicology; (USA), Journal Name: Bulletin of Environmental Contamination and Toxicology; (USA) Vol. 44:2; ISSN 0007-4861; ISSN BECTA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BIOCHEMISTRY
CHEMICAL REACTIONS
CHEMISTRY
CHLORINATION
CHROMATOGRAPHY
ENZYME ACTIVITY
ENZYMES
FUNGI
GAS CHROMATOGRAPHY
HALOGENATION
HYDROXY COMPOUNDS
MASS SPECTROSCOPY
ORGANIC COMPOUNDS
OXIDOREDUCTASES
PEROXIDASES
PHENOLS
PLANTS
SEPARATION PROCESSES
SPECTROSCOPY